The psychological impact of COVID‐19 pandemic on patients with neuroendocrine tumors: Between resilience and vulnerability
| Autor: | Barbara Mandriani, Alessandra Bracigliano, Brunella Amoruso, Valentina Felici, Francesco Perri, Salvatore Tafuto, Chiara Esposto, Rossella Lippolis, Cira Forte, Eleonora Lauricella, Eleonora Pelle, Mauro Cives, Camillo Porta, Ottavia Clemente |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
carcinoid
post‐traumatic stress disorder medicine.medical_specialty Endocrine and Autonomic Systems business.industry Endocrinology Diabetes and Metabolism Psychological intervention Odds ratio anxiety Confidence interval HRQoL Cellular and Molecular Neuroscience Mental distress Endocrinology Quality of life Internal medicine depression TRANSLATIONAL AND CLINICAL NEUROENDOCRINOLOGY Medicine Marital status Anxiety Original Article medicine.symptom business Depression (differential diagnoses) |
| Zdroj: | Journal of Neuroendocrinology |
| ISSN: | 1365-2826 0953-8194 |
| Popis: | The COVID‐19 pandemic has added another layer of complexity to the fears of patients with neuroendocrine tumors (NETs). Little is known regarding the psychological impact of the COVID‐19 outbreak on patients with gastroenteropancreatic or bronchopulmonary (BP) NETs. We longitudinally surveyed the mental symptoms and concerns of NET patients during the plateau phase of the first (W1) and second epidemic waves (W2) in Italy. Seven specific constructs (depression, anxiety, stress, health‐related quality of life, NET‐related quality of life, patient–physician relationship, psychological distress) were investigated using validated screening instruments, including DASS‐21, EORTC QLQ‐C30, EORTC QLQ GI.NET21, PDRQ9 and IES‐R. We enrolled 197 patients (98 males) with a median age of 62 years. The majority of the patients had G1/G2 neoplasms. Some 38% of the patients were on active treatment. At W1, the prevalence of depression, anxiety and stress was 32%, 36% and 26% respectively. The frequency of depression and anxiety increased to 38% and 41% at W2, whereas no modifications were recorded in the frequency of stress. Poor educational status was associated with higher levels of anxiety at both W1 (odds ratio [OR] = 1.33 ± 0.22; p = .07) and W2 (OR = 1.45 ± 0.26; p = .03). Notably, post‐traumatic stress symptoms were observed in the 58% of the patients, and both single marital status (OR = 0.16, 95% confidence interval [CI] = 0.06–0.48; p = .0009) and low levels of formal education (OR = 0.47, 95% CI = 0.23–0.99; p = .05) predicted their occurrence. No significant deteriorations of health‐related quality of life domains were observed from W1 to W2. High patient care satisfaction was documented despite the changes in health systems resource allocation. NET patients have an increased risk of developing post‐traumatic stress symptoms as result of the COVID‐19 pandemic. Specific screening measures and psychological interventions should be implemented in NET clinics to prevent, recognize and treat mental distress in this vulnerable population. NET patients have an increased risk of developing post‐traumatic stress symptoms as result of the COVID‐19 pandemic. Specific screening measures and psychological interventions should be implemented in NET clinics to prevent, recognize and treat mental distress in this vulnerable population. |
| Databáze: | OpenAIRE |
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