Fluid dynamic analysis in a human left anterior descending coronary artery with arterial motion
| Autor: | Sarah C. Vigmostad, Andreas Wahle, Mark E. Olszewski, Krishnan B. Chandran, Y. G. Lai, Theresa M. H. Brennan, James D. Rossen, Milan Sonka, Sharan Ramaswamy, K.C. Braddy |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Finite Element Analysis Biomedical Engineering Pulsatile flow Coronary Artery Disease Anterior Descending Coronary Artery Coronary circulation Imaging Three-Dimensional Internal medicine Coronary Circulation medicine Shear stress Fluid dynamics Humans Computer Simulation Dynamics (mechanics) Models Cardiovascular Numerical Analysis Computer-Assisted Blood flow Coronary Vessels Radiography medicine.anatomical_structure Pulsatile Flow Coronary vessel cardiovascular system Cardiology Stress Mechanical Shear Strength Geology Blood Flow Velocity Biomedical engineering |
| Zdroj: | Annals of biomedical engineering. 32(12) |
| ISSN: | 0090-6964 |
| Popis: | A computational fluid dynamic (CFD) analysis is pre sented to describe local flow dynamics in both 3-D spatial and 4-D spatial and temporal domains from reconstructions of intravascular ultrasound (IVUS) and bi-plane angiographic fusion images. A left anterior descending (LAD) coronary artery segment geometry was accurately reconstructed and subsequently its motion was incorporated into the CFD model. The results indicate that the incorporation of motion had appreciable effects on blood flow patterns. The velocity profiles in the region of a stenosis and the circumferential distribution of the axial wall shear stress (WSS) patterns in the vessel are altered with the wall motion introduced in the simulation. The time-averaged axial WSS between simulations of steady flow and unsteady flow without arterial motion were comparable (-0.3 to 13.7 Pa in unsteady flow versus -0.2 to 10.1 Pa in steady flow) while the magnitudes decreased when motion was introduced (0.3-4.5 Pa). The arterial wall motion affects the time-mean WSS and the oscillatory shear index in the coronary vessel fluid dynamics and may provide more realistic predictions on the progression of atherosclerotic disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink