LETHAL EFFECT AND VISIBLE IRRADIATION DAMAGE
Autor: | V. V. Brunst |
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Rok vydání: | 1968 |
Předmět: |
Pathology
medicine.medical_specialty Urodela Eye Cytology medicine Animals Radiology Nuclear Medicine and imaging Irradiation Skin Larva Blood Cells Hatching business.industry Lethal dose General Medicine Anatomy Epithelium Intestines Radiation Injuries Experimental medicine.anatomical_structure Jaw Liver Giant cell Simple squamous epithelium business Head Spleen |
Zdroj: | American Journal of Roentgenology. 102:53-70 |
ISSN: | 1546-3141 0361-803X |
DOI: | 10.2214/ajr.102.1.53 |
Popis: | The present study utilized 650 axolotls (Siredon mexicanum), 12 days after hatching. In one series of experiments involving 500 animals from one spawning, nine groups of 50 animals each received totalbody irradiation with 200, 300, 400, 600, 800, 1,000, 1,500, 2,000, and 3,000 r, respectively. In another series of experiments involving 150 animals from another spawning, two groups of 50 animals each received 100 and 200 r, respectively. In each series of experiments, the remaining 50 animals served as untreated controls.1. All doses from 200 r up very definitely suppressed growth.2. The response of the skin epithelium to irradiation, even with a dose as large as 3,000 r, was highly diverse, and at most only partial. Not a single animal with totally damaged skin epithelium could be found, but the skin epithelium was completely normal in some instances even after 3,000 r. In some areas of the skin epithelium of irradiated animals, giant cells developed and the simple squamous epithelium was transformed into... |
Databáze: | OpenAIRE |
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