Vestibular and radiological characteristics of children affected by unilateral auditory neuropathy spectrum disorder
| Autor: | Céline Laurent, Benoît Devroede, Amelia Favoreel, Paul Deltenre, Georges Fayad |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Vestibular evoked myogenic potential Auditory neuropathy Otoacoustic Emissions Spontaneous Otoacoustic emission Audiology Auditory neuropathy spectrum disorder otorhinolaryngologic diseases medicine Evoked Potentials Auditory Brain Stem Humans Hearing Loss Central Evoked potential Vestibular system business.industry Cochlear nerve General Medicine medicine.disease Otorhinolaryngology Pediatrics Perinatology and Child Health Female sense organs Vestibule Labyrinth Cochlear microphonic potential business |
| Zdroj: | International journal of pediatric otorhinolaryngology. 152 |
| ISSN: | 1872-8464 |
| Popis: | Objective Auditory neuropathy spectrum disorders (ANSD) are defined by the association of a preserved outer hair cell function and an impaired auditory nerve neural response, and present mostly bilaterally. Unilateral ANSD are consequently only seldom described, and most frequently as isolated cases. This study aims to describe the audiological, vestibular and radiological characteristics of a population of children with unilateral ANSD. Material and methods We isolated 22 patients with unilateral ANSD, 12 boys and 10 girls from 0 to 95 months, in a database of auditory evoked potentials. We reviewed the audiological, radiological and vestibular assessments. The audiological assessment included tympanometry, otoacoustic emission recording and auditory evoked potential. Otolithic function was assessed by performing cervical vestibular evoked myogenic potential. The canal function was determined by video head impulse test and/or caloric test. The radiological evaluation consisted of an MRI of the internal auditory canal. Results Many patients with a type A tympanometry had no response to otoacoustic emission (53,8%), in the presence of a cochlear microphonic potential. Vestibular assessment was performed in 9 of the 22 patients. 4 children had impaired otolithic and/or canal function. MRI evaluation of the inner ear was performed in 18 patients. Aplasia or hypoplasia of the cochlear nerve was found in 17 of them. MRI showed additional vestibular or brainstem abnormalities in 7 of the 18 children. All children with impaired vestibular function had vestibular or brainstem radiological alterations in addition to cochlear branch aplasia or hypoplasia. Conclusions Radiological and vestibular abnormalities are common in children with unilateral ANSD and suggest that a radiological and vestibular assessment is required. |
| Databáze: | OpenAIRE |
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