A novel intermittent negative air pressure device ameliorates obstructive sleep apnea syndrome in adults
| Autor: | Tien Jen Liu, Tzu Chun Hung, Kuang Hui Sun, Christian Guilleminault, Wen Ko Su, Bo Nien Chen, Wen Yeh Hsieh |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Neurology Polysomnography medicine.medical_treatment Ventilators Negative-Pressure Internal medicine Humans Medicine Continuous positive airway pressure Sleep Apnea Obstructive Continuous Positive Airway Pressure medicine.diagnostic_test business.industry Middle Aged Airway obstruction medicine.disease nervous system diseases respiratory tract diseases Obstructive sleep apnea Treatment Outcome Otorhinolaryngology Apnea–hypopnea index Cardiology Patient Compliance Female Neurology (clinical) business Body mass index |
| Zdroj: | Sleep and Breathing. 23:849-856 |
| ISSN: | 1522-1709 1520-9512 |
| DOI: | 10.1007/s11325-018-01778-z |
| Popis: | Patients with obstructive sleep apnea syndrome (OSAS) have difficulties in compliance with continuous positive airway pressure (CPAP) and the treatment outcome is heterogeneous. We proposed a proof-of-concept study of a novel intermittent negative air pressure (iNAP®) device for physicians to apply on patients who have failed or refused to use CPAP. The iNAP® device retains the tongue and the soft palate in a forward position to decrease airway obstruction. A full nightly usage with the device was evaluated with polysomnography. Subgrouping by baseline apnea–hypopnea index (AHI) and body mass index (BMI) with different treatment response criteria was applied to characterize the responder group of this novel device. Thirty-five patients were enrolled: age 41.9 ± 12.2 years (mean ± standard deviation), BMI 26.6 ± 4.3 kg/m2, AHI 41.4 ± 24.3 events/h, and oxygen desaturation index (ODI) 40.9 ± 24.4 events/h at baseline. AHI and ODI were significantly decreased (p |
| Databáze: | OpenAIRE |
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