Postnatal unilateral pelviureteral junction obstruction: Impact of pyeloplasty and conservative management on renal function
| Autor: | Mohamed T. El-Sherbiny, Mohamed Dawaba, Hosam M. Gad, Ahmed M. Ghaly, Ahmed A. Shokeir, Ashraf T. Hafez, Mohamed Saida, Mohamed A. Taha |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Pyeloplasty Urology medicine.medical_treatment Renal function Hydronephrosis Kidney urologic and male genital diseases Asymptomatic Prenatal Diagnosis Internal medicine Statistical significance medicine Humans Kidney Pelvis Child Prospective cohort study business.industry medicine.disease Surgery medicine.anatomical_structure Child Preschool Female medicine.symptom business Radioisotope Renography Glomerular Filtration Rate Ureteral Obstruction Kidney disease |
| Zdroj: | Urology. 65:980-985 |
| ISSN: | 0090-4295 |
| DOI: | 10.1016/j.urology.2004.12.065 |
| Popis: | OBJECTIVES To study the effect of pyeloplasty and conservative management on renal function in children with pelviureteral junction obstruction. METHODS This prospective study included 65 children postnatally diagnosed with unilateral pelviureteral junction obstruction. On the basis of the patients' symptoms and technetium-99m diethylenetriamine pentaacetic acid renal isotope scan findings, symptomatic patients or those with split function of the corresponding kidney of 40% or less were assigned to group 1 (n = 35) and underwent pyeloplasty. Asymptomatic patients with split function greater than 40% (group 2, n = 30) were treated conservatively. Patients who showed deterioration of renal function underwent pyeloplasty. The effect of both lines of treatment on renal function was evaluated. RESULTS After pyeloplasty, group 1 had improvement in the glomerular filtration rate (GFR) in 30 (85.7%), stabilization in 2 (5.7%), and deterioration in 3 (8.6%) patients. In group 1, the comparison between the mean value of the baseline GFR (17.1 +/- 7.7 mL/min) and its mean value at follow-up (28 +/- 6.3 mL/min) showed an increase of statistical significance (P |
| Databáze: | OpenAIRE |
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