Chronic fatigue syndrome (CFS): Suggestions for a nutritional treatment in the therapeutic approach

Autor: Joeri J Pen, Maryam Dadar, Geir Bjørklund, Salvatore Chirumbolo, Jan Aaseth
Přispěvatelé: Pathology/molecular and cellular medicine, Diabetes Clinic
Rok vydání: 2019
Předmět:
musculoskeletal diseases
0301 basic medicine
Vitamin
Exacerbation
T-Lymphocytes
Nutrients/administration & dosage
Oxidative Stress/drug effects
Immunoglobulins
RM1-950
Disease
medicine.disease_cause
dietary supplements
03 medical and health sciences
chemistry.chemical_compound
Therapeutic approach
Cytokines/immunology
T-Lymphocytes/drug effects
0302 clinical medicine
Chronic fatigue syndrome
Nutrients
Cytokines
Lymphocyte transformation
Delayed hypersensitivity
medicine
Humans
Gastrointestinal Microbiome/drug effects
Fatigue Syndrome
Chronic/diet therapy
Pharmacology
Coenzyme Q10
Fatigue Syndrome
Chronic
business.industry
General Medicine
Immune dysregulation
medicine.disease
Gastrointestinal Microbiome
Oxidative Stress
030104 developmental biology
chemistry
030220 oncology & carcinogenesis
Immunology
Therapeutics. Pharmacology
business
Zdroj: Biomedicine & Pharmacotherapy, Vol 109, Iss, Pp 1000-1007 (2019)
Biomedicine and Pharmacotherapy
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2018.10.076
Popis: Chronic fatigue syndrome (CFS) is known as a multi-systemic and complex illness, which induces fatigue and long-term disability in educational, occupational, social, or personal activities. The diagnosis of this disease is difficult, due to lacking a proper and suited diagnostic laboratory test, besides to its multifaceted symptoms. Numerous factors, including environmental and immunological issues, and a large spectrum of CFS symptoms, have recently been reported. In this review, we focus on the nutritional intervention in CFS, discussing the many immunological, environmental, and nutritional aspects currently investigated about this disease. Changes in immunoglobulin levels, cytokine profiles and B- and T- cell phenotype and declined cytotoxicity of natural killer cells, are commonly reported features of immune dysregulation in CFS. Also, some nutrient deficiencies (vitamin C, vitamin B complex, sodium, magnesium, zinc, folic acid, l-carnitine, l-tryptophan, essential fatty acids, and coenzyme Q10) appear to be important in the severity and exacerbation of CFS symptoms. This review highlights a far-driven analysis of mineral and vitamin deficiencies among CFS patients.
Databáze: OpenAIRE
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