Incidence of Symptomatic Congenital Toxoplasmosis During Ten Years in a Brazilian Hospital
| Autor: | Jacobo Melamed Cattan, Luciana Friedrich, Adrianne Rahde Bischoff, Flávio Antonio de Freitas Uberti |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Microbiology (medical) Pediatrics medicine.medical_specialty Adolescent 030231 tropical medicine Population Toxoplasmosis Congenital Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Humans Medicine Seroprevalence 030212 general & internal medicine Pregnancy Complications Infectious Young adult education Retrospective Studies education.field_of_study business.industry Transmission (medicine) Incidence (epidemiology) Chorioretinitis Retrospective cohort study medicine.disease Hospitals Infectious Disease Transmission Vertical Infectious Diseases Pediatrics Perinatology and Child Health Female business Brazil |
| Zdroj: | Pediatric Infectious Disease Journal. 35:1313-1316 |
| ISSN: | 0891-3668 |
| DOI: | 10.1097/inf.0000000000001307 |
| Popis: | Population seroprevalence and rates of mother-to-child transmission are important in determining the incidence of congenital toxoplasmosis. (CT) Mother-to-child transmission depends on the timing of acute maternal infection and treatment during pregnancy. The incidence of CT varies widely across geographic regions, ranging from 1 to 10 cases per 10,000 live births. The incidence of symptomatic disease varies from 0.15 to 0.34 cases per 10,000.This is a review of patients treated at a pediatric CT clinic at a university hospital in the south of Brazil, from 2004 to 2014.The annual incidence of CT varied from 0 to 14 cases per 10,000 live births, with a mean incidence of 6 cases per 10,000 during the 10 years studied (CI 95%: 3.02-8.91). The incidence of symptomatic CT varied from 0 to 9 cases per 10,000 live births, with a mean incidence of 5 per 10,000 (CI 95%: 2.44-6.94). There were 5 (14.3%) asymptomatic cases. The main findings were retinochoroiditis (54%), intracranial calcifications (37.5%) and altered cerebrospinal fluid (37.5%).The incidence of CT and the rate of symptomatic cases were in accordance with the previous data from other studies in Brazil, being significantly higher than in previous North American and European studies. |
| Databáze: | OpenAIRE |
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