Chronic Extrinsic Cardiac Denervation by Regional Neural Ablation
| Autor: | J. Richard Crout, Joseph W. Gilbert, Robert D. Bloodwell, Theodore Cooper |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
Denervation
Physiology business.industry Myocardium medicine.medical_treatment Mediastinum Heart Stimulation Isolated heart Ablation Transplantation Catecholamines medicine.anatomical_structure Cardiac denervation Anesthesia medicine Extrinsic denervation Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation Research. 9:275-281 |
| ISSN: | 1524-4571 0009-7330 |
| Popis: | A technique for complete extrinsic denervation of the heart by the ablation of neural structures in the mediastinum is described. The completeness of denervation was verified by direct electrical stimulation of the main vagal and sympathetic trunks. Total deple tion of myocardial catecholamines followed the procedure in chronic survivors. Animals prepared in this manner are useful in the study of the neurologically isolated heart and simulate this aspect of the problem of cardiac transplantation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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