Confirmed circulation of SARS-CoV-2 in Irish blood donors prior to first national notification of infection
| Autor: | Stephen Field, Paul Holder, Dermot Coyne, Alex Carterson, Niamh O'Flaherty, Padraig Williams, Dearbhla Butler, Allison Waters, Louise Pomeroy |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Blood transfusion Epidemiology Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medicine.medical_treatment Population Seroprevalence Blood Donors Antibodies Viral Article Irish Seroepidemiologic Studies Virology Internal medicine Pandemic Medicine Humans education Pandemics education.field_of_study biology business.industry SARS-CoV-2 COVID-19 language.human_language Infectious Diseases Blood language biology.protein Antibody business Ireland Donor |
| Zdroj: | Journal of Clinical Virology |
| ISSN: | 1873-5967 |
| Popis: | INTRODUCTION Blood donor studies offer a unique opportunity to screen healthy populations for the presence of antibodies to emerging infections. We describe the use of blood donor specimens to track the 'first-wave' of the COVID-19 pandemic in Ireland. METHODOLOGY A random selection of donor samples received by the Irish Blood Transfusion Service (IBTS) between February and September 2020 (n = 8,509) were screened by multiple commercial SARs-CoV-2 antibody assays. The antibody detection rate was adjusted to the population to determine the SARS-CoV-2 seroprevalence in Ireland. RESULTS SARS-CoV-2 antibody detection rose significantly during the first peak of COVID-19 infection, increasing from 0.3% in March, to 2.9% in April (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect