On heterogeneity of treatment effects and clinical freedom
| Autor: | C. Avendaño-Solá, J. A. Sacristán |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Freedom
medicine.medical_specialty education.field_of_study Evidence-Based Medicine business.industry Population Alternative medicine Cornerstone General Medicine Health outcomes law.invention Clinical Practice Clinical research Randomized controlled trial law Family medicine Humans Medicine Practice Patterns Physicians' business education Psychiatry Randomized Controlled Trials as Topic |
| Zdroj: | International Journal of Clinical Practice. 69:6-8 |
| ISSN: | 1368-5031 |
| DOI: | 10.1111/ijcp.12537 |
| Popis: | Three decades ago, John R Hampton announced the death of clinical freedom. Since then, evidence-based medicine has been the predominant paradigm in clinical research. By applying a population-based approach, the randomised controlled trial has become the cornerstone for demonstrating the overall effect of a treatment and for developing guidelines. The new patient-centred medicine movement is rediscovering the important implications of heterogeneity of treatment effects for clinical practice and that a better understanding of such variability can contribute to improve health outcomes for individual patients through practicing a science-based clinical freedom. |
| Databáze: | OpenAIRE |
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