Polysaccharide from Seeds of Plantago asiatica L. Affects Lipid Metabolism and Colon Microbiota of Mouse
| Autor: | Joshua Gong, Shaoping Nie, Qi-Meng Wu, Steve W. Cui, Zhi-Hong Fu, Jielun Hu, Mingyong Xie, Chang Li |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Colon Lactobacillus fermentum ved/biology.organism_classification_rank.species Plantago asiatica Polysaccharide Microbiology Mice Blood serum Polysaccharides Animals Eubacterium Plantago chemistry.chemical_classification Bifidobacterium bifidum Bacteria biology Plant Extracts ved/biology Microbiota food and beverages Lipid metabolism General Chemistry Lipid Metabolism biology.organism_classification Lactobacillus reuteri chemistry Seeds Female General Agricultural and Biological Sciences |
| Zdroj: | Journal of Agricultural and Food Chemistry. 62:229-234 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/jf4040942 |
| Popis: | Polysaccharide from the seeds of Plantago asiatica L. was given via oral administration to mice (0.4 g/kg body weight, 30 days) to observe its effects on mouse nutrient metabolism and colon microbiota. It was found the polysaccharide intake could lower the apparent absorption of lipid. Total triglyceride, cholesterol, and atherogenic index in blood serum with total lipid and cholesterol levels in liver of polysaccharide group mice were all significantly lower than those of the control group (p < 0.05). Furthermore, the effect of the polysaccharide intake on mouse colon bacterial communities was investigated. Mice from the polysaccharide group showed a higher colon bacterial diversity than the control group. Bacteroides sp., Eubacterium sp., butyrate-producing bacteria Butyrivibrio sp., and probiotics Bifidobacterium bifidum , Lactobacillus fermentum , and Lactobacillus reuteri in mouse colon were all increased after polysaccharide intake. These indicated that the intake of polysaccharide from P. asiatica L. could be beneficial for lipid metabolism and colon microbiota. |
| Databáze: | OpenAIRE |
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