Parotid salivary sodium levels of Sjögren's syndrome patients suggest B-cell mediated epithelial sodium channel disruption

Autor:	Sarah Pringle, Bas Berkhof, Marthe van Ginkel, Silvia Liefers, Bert van der Vegt, fred spijkervet, Hendrika Bootsma, Arjan Vissink, Kroese, Frans G. M.
Přispěvatelé:	Translational Immunology Groningen (TRIGR), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Personalized Healthcare Technology (PHT)
Předmět:	B cells SIALOCHEMISTRY FLOW Immunology ENAC Sodium GLANDS stomatognathic diseases Sjogren's Syndrome Rheumatology stomatognathic system epithelia sodium channel FLUID TRANSPORT Immunology and Allergy Humans Parotid Gland DECREASES EXPRESSION Epithelial Sodium Channels Saliva SIALOMETRY
Zdroj:	University of Groningen Clinical and Experimental Rheumatology, 39(6, Suppl.133), S30-S38. CLINICAL & EXPER RHEUMATOLOGY
ISSN:	0392-856X
Popis:	Patients with primary Sjögren's syndrome (SS) suffer widely from lack of saliva production. Here we investigate potential mechanisms underpinning changes in SS patient saliva composition. Sodium concentration was significantly higher in all saliva samples collected: unstimulated submandibular/sublingual (SmSl) saliva (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115b70f6a35bd5c4b75e84ade6e5a23d https://research.rug.nl/en/publications/3bf10622-025e-4169-8e2f-446c04011148 Zobrazit plný text záznamu