Risk factors for Barrett's esophagus: A case-control study
| Autor: | Conio, Massimo, Filiberti, Rosangela, Blanchi, Sabrina, Ferraris, Roberto, Marchi, Santino, Ravelli, Paolo, Lapertosa, Gabriella, Iaquinto, Gaetano, Sablich, Renato, Gusmaroli, Riccardo, Aste, Hugo, Giacosa, Attilio, Conio, M., Munizzi, F., Aste, H., Giacosa, A., Ferraris, R., Fracchia, M., Pera, A., Marchi, S., Costa, F., Rivelli, P., Missale, Guido, Cestari, Renzo, Lapertosa, G., Fiocca, R., D'Onofrio, V., Iaquinto, G., Sablich, R., Lacchin, T., Benedetti, G., Gusmaroli, R. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Cancer Research Adolescent GOSPE Gastroenterology Hiatal hernia Barrett Esophagus Barrett's esophagus Esophagitis GERD Italy Risk factors Oncology Internal medicine Surveys and Questionnaires Odds Ratio Medicine Humans Medical history Risk factor Aged Aged 80 and over business.industry Esophageal disease Incidence Heartburn Middle Aged medicine.disease humanities digestive system diseases Case-Control Studies Quality of Life Female Esophagoscopy medicine.symptom business |
| Popis: | Barrett's esophagus (BE) is an acquired disorder due to chronic gastroesophageal reflux. Environmental factors seem to play an important role in the pathogenesis of BE, especially in Western society. A multicenter case-control study was carried out between February 1995 and April 1999 in 8 Italian Departments of Gastroenterology gathered in a study group (GOSPE), in order to analyze the influence of some individual characteristics and life-style habits on the occurrence of BE. Three groups of patients were studied: 149 patients with BE, 143 patients with esophagitis (E) and 308 hospital controls (C) with acute, non-neoplastic, non-gastroenterological conditions. The diagnosis of BE was based on endoscopy and histology. E was defined by the Savary classification (grade I–III). Data collection was performed by using a questionnaire that focused on smoking, coffee and alcohol consumption, medical history, drugs history, gastroesophageal reflux disease (GERD) symptoms (heartburn, regurgitation) and socio-economic status. Multivariate analysis showed that the frequency of weekly GERD symptoms was significantly associated with both BE and E (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|