Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19–Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity — Nine States, January–September 2021
| Autor: | Rachael M. Porter, I-Chia Liao, Palak Patel, Nimish R Valvi, Duck-Hye Yang, Sue Reynolds, Ned Lewis, Patrick K. Mitchell, Catherine H Bozio, Malini B. DeSilva, Sarah Ball, Manjusha Gaglani, Brian E. Dixon, Kristin Goddard, Toan C Ong, Edward Stenehjem, Kristen A Butterfield, Stephanie A. Irving, Charlene McEvoy, Bruce Fireman, Anupam B Kharbanda, Andrea Steffens, Rebecca J Birch, Nancy Grisel, Peter J Embi, Meredith McMorrow, Julie Arndorfer, Shaun J. Grannis, Jennifer R. Verani, Natalie Olson, Kempapura Murthy, Jill M. Ferdinands, Elizabeth A Rowley, Alicia M. Fry, Jungmi Han, Lenee Blanton, Mark G. Thompson, Eric P Griggs, Chandni Raiyani, Kristin Dascomb, William F. Fadel, Suchitra Rao, Matthew E Levy, Karthik Natarajan, Michelle A Barron, Nicola P. Klein, Eduardo Azziz-Baumgartner, Sarah E Reese, Ousseny Zerbo, Stephanie J. Schrag, Monica Dickerson, Allison L. Naleway, Jeremiah Williams |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty COVID-19 Vaccines Health (social science) Adolescent Epidemiology Health Toxicology and Mutagenesis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Virus Odds Young Adult Health Information Management Immunity Internal medicine Humans Medicine Full Report Young adult Aged Aged 80 and over Vaccines Synthetic SARS-CoV-2 business.industry COVID-19 General Medicine Odds ratio Middle Aged Confidence interval Hospitalization Vaccination Female Laboratories business |
| Zdroj: | Morbidity and Mortality Weekly Report |
| ISSN: | 1545-861X 0149-2195 |
| DOI: | 10.15585/mmwr.mm7044e1 |
| Popis: | Previous infection with SARS-CoV-2 (the virus that causes COVID-19) or COVID-19 vaccination can provide immunity and protection from subsequent SARS-CoV-2 infection and illness. CDC used data from the VISION Network* to examine hospitalizations in adults with COVID-19-like illness and compared the odds of receiving a positive SARS-CoV-2 test result, and thus having laboratory-confirmed COVID-19, between unvaccinated patients with a previous SARS-CoV-2 infection occurring 90-179 days before COVID-19-like illness hospitalization, and patients who were fully vaccinated with an mRNA COVID-19 vaccine 90-179 days before hospitalization with no previous documented SARS-CoV-2 infection. Hospitalized adults aged ≥18 years with COVID-19-like illness were included if they had received testing at least twice: once associated with a COVID-19-like illness hospitalization during January-September 2021 and at least once earlier (since February 1, 2020, and ≥14 days before that hospitalization). Among COVID-19-like illness hospitalizations in persons whose previous infection or vaccination occurred 90-179 days earlier, the odds of laboratory-confirmed COVID-19 (adjusted for sociodemographic and health characteristics) among unvaccinated, previously infected adults were higher than the odds among fully vaccinated recipients of an mRNA COVID-19 vaccine with no previous documented infection (adjusted odds ratio [aOR] = 5.49; 95% confidence interval [CI] = 2.75-10.99). These findings suggest that among hospitalized adults with COVID-19-like illness whose previous infection or vaccination occurred 90-179 days earlier, vaccine-induced immunity was more protective than infection-induced immunity against laboratory-confirmed COVID-19. All eligible persons should be vaccinated against COVID-19 as soon as possible, including unvaccinated persons previously infected with SARS-CoV-2. |
| Databáze: | OpenAIRE |
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