Selective generation of gut-tropic T cells in gut-associated lymphoid tissues: requirement for GALT dendritic cells and adjuvant
| Autor: | Marcus Svensson, Marc-André Wurbel, Bernard Malissen, William W. Agace, Gabriel Márquez, Bengt Johansson-Lindbom |
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| Rok vydání: | 2005 |
| Předmět: |
Chemokine
Lymphoid Tissue T-Lymphocytes Receptors Lymphocyte Homing CCR9 Antigen-Presenting Cells General Biochemistry Genetics and Molecular Biology Chemokine receptor History and Philosophy of Science Intestinal mucosa Animals Humans Intestinal Mucosa Antigen-presenting cell Immunity Mucosal Inflammation biology Cell adhesion molecule Effector General Neuroscience Dendritic Cells Cell biology CCL20 Immunology biology.protein Chemokines |
| Zdroj: | Annals of the New York Academy of Sciences. 1029 |
| ISSN: | 0077-8923 |
| Popis: | To gain entry into peripheral tissues, effector T lymphocytes express specific combinations of adhesion molecules and chemokine receptors. Expression of these are induced during activation in regional secondary lymphoid organs. Herein, we describe a role for GALT DCs in the generation of CCR9(+) alpha(4)beta(7)(+) gut tropic lymphocytes. |
| Databáze: | OpenAIRE |
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