Absence of Central Microtubules and Transposition in the Ciliary Apparatus of Three Siblings
| Autor: | F. Rodríguez de Castro, G. Bautista-Harris, Pedro Cabrera-Navarro, I. Santana-Benitez, G. Julià-Serdà |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Infertility Chronic bronchitis Pathology medicine.medical_specialty Bronchi Microtubules Transposition (music) Pathogenesis Humans Medicine Cilia Bronchitis business.industry Cilium Respiratory disease respiratory system medicine.disease Trachea Microscopy Electron Situs inversus Chronic Disease Female business Ciliary Motility Disorders |
| Zdroj: | Respiration. 67:449-452 |
| ISSN: | 1423-0356 0025-7931 |
| DOI: | 10.1159/000029547 |
| Popis: | We studied the cases of three siblings with a history of chronic bronchitis and infertility. The electron-microscopic investigation of the tracheal and bronchial biopsies showed a ciliary defect consisting in the absence of the central microtubules and the transposition of a peripheral doublet. This is a rare and infrequently reported abnormality included in the primary ciliary diskinesia syndrome. |
| Databáze: | OpenAIRE |
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