Frailty: A cost incurred by reproduction?
| Autor: | Mark D. Chatfield, Ruth E. Hubbard, Nancye M. Peel, Emily H Gordon, I. A. Lang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Senescence Aging Longitudinal study Epidemiology Cross-sectional study Health Status media_common.quotation_subject Longevity lcsh:Medicine 030209 endocrinology & metabolism Fertility Article 03 medical and health sciences 0302 clinical medicine Humans Longitudinal Studies 030212 general & internal medicine lcsh:Science Aged media_common Aged 80 and over Sex Characteristics Multidisciplinary Natural selection Frailty Reproduction lcsh:R Fecundity Ageing Cross-Sectional Studies Female lcsh:Q Psychology Demography Sex characteristics |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-67009-2 |
| Popis: | Evolutionary theories of senescence, such as the ‘disposable soma’ theory, propose that natural selection trades late survival for early fecundity. ‘Frailty’, a multidimensional measure of health status, may help to better define the long-term consequences of reproduction. We examined the relationship between parity and later life frailty (as measured by the Frailty Index) in a sample of 3,534 adults aged 65 years and older who participated in the English Longitudinal Study of Ageing. We found that the most parous adults were the most frail and that the parity-frailty relationship was similar for both sexes. Whilst this study provided some evidence for a ‘parity-frailty trade-off’, there was little support for our hypothesis that the physiological costs of childbearing influence later life frailty. Rather, behavioural and social factors associated with rearing many children may have contributed to the development of frailty in both sexes. |
| Databáze: | OpenAIRE |
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