Comparison of fMRI activation as measured with gradient- and spin-echo EPI during visual perception
| Autor: | Conny F. Schmidt, Peter Boesiger, Alumit Ishai |
|---|---|
| Přispěvatelé: | University of Zurich, Ishai, A |
| Rok vydání: | 2005 |
| Předmět: |
2805 Cognitive Neuroscience
Adult Diagnostic Imaging Male Visual perception genetic structures Cognitive Neuroscience Inferior frontal gyrus 610 Medicine & health behavioral disciplines and activities Amygdala 10043 Clinic for Neuroradiology Face perception Image Processing Computer-Assisted medicine Cluster Analysis Humans Attention Cerebral Cortex Physics Brain Mapping Fusiform gyrus Electron Spin Resonance Spectroscopy Recognition Psychology Superior temporal sulcus Magnetic Resonance Imaging Emotional lateralization medicine.anatomical_structure nervous system Neurology 2808 Neurology Face Visual Perception Female Orbitofrontal cortex Artifacts Neuroscience Photic Stimulation psychological phenomena and processes |
| Zdroj: | NeuroImage. 26:852-859 |
| ISSN: | 1053-8119 |
| DOI: | 10.1016/j.neuroimage.2005.02.043 |
| Popis: | In this study, we compared fMRI activation measured with gradient- and spin-echo-based fMRI during visual perception of faces, which is mediated by neural activation within a distributed cortical network. With both fMRI techniques, bilateral activation was observed in multiple regions including the inferior occipital gyrus, fusiform gyrus, superior temporal sulcus, amygdala, inferior frontal gyrus, and orbitofrontal cortex. When compared with the gradient-echo sequence, activation measured with the spin-echo sequence was significantly reduced. This decrease was manifested by smaller cluster size, lower statistical significance, smaller amplitude of the fMRI signal, and smaller number of subjects who showed activation in all face-responsive regions. In orbitofrontal cortex, a region prone to susceptibility-related signal dephasing, the spin-echo acquisition considerably restored the signal, but did not reveal stronger activation when compared with the gradient-echo acquisition. Our data indicate that optimized GE sequences that reduce susceptibility artefacts are sufficient to detect activation in regions such as the orbitofrontal cortex. |
| Databáze: | OpenAIRE |
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