ICD Therapy Confers No Survival Advantage in a Global LVAD Population: Insights from the Trans-Atlantic Registry on VAD and Transplant (TRAViATA)
| Autor: | Oscar Ö. Braun, Enrico Perna, Quan M. Bui, Cynthia Partida, Antonio Loforte, Marco Masetti, Johan Nilsson, Eric Adler, M. Frigerio, Michela Brambatti, E. Ammirati, V. Pretorius, C M Van De Heyning, Filip Rega, D. De Bock, Palak Shah, Manlio Cipriani, Jonathan Minto, Claudio Russo, Grunde Gjesdal, Maja Cikes, Nina Jakuš, Luciano Potena, K. Van den Bossche, Caroline Sterken, Philippe Timmermans, Jasper J. Brugts, Kimberly N. Hong, Liviu Klein, R. Sing, Jesse F. Veenis |
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| Přispěvatelé: | Cardiology |
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Transplantation education.field_of_study medicine.medical_specialty business.industry Population Retrospective cohort study equipment and supplies Icd therapy Discontinuation Emergency medicine Survival advantage Medicine Surgery In patient Cardiology and Cardiovascular Medicine education business Survival analysis |
| Zdroj: | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 39(4) |
| ISSN: | 1053-2498 |
| Popis: | PURPOSE: There are conflicting data related to the use of implantable cardioverter-defibrillators (ICDs) in patients supported with continuous-flow ventricular assist devices (LVADs). Several US studies have shown a neutral effect on mortality, whereas a recent European study suggested better outcomes in LVAD patients who have an ICD. We aimed to investigate the benefit of ICDs in patients bridged to transplant with a LVAD in the TRans-Atlantic registry on VAd and TrAnsplant (TRAViATA). METHODS: Data from consecutive patients that received a LVAD as a bridge to transplantation between January 2008 and April 2017 were collected in 7 EU (n=299) and 3 US centers (n=225). Survival analysis was performed using Kaplan-Meier and Cox proportion hazard regression analysis. Patients were censored at time of transplantation. RESULTS: Patients with an ICD at the time of LVAD (n=350) implantation were older (56 vs. 53 years, p |
| Databáze: | OpenAIRE |
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