A Rare Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus
| Autor: | Ghazala Hanif, Attia Bari, Iqbal Bano, Uzma Jabeen, Fatima Zeeshan, Ahsan Waheed Rathore |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Fever Nifedipine Vasodilator Agents Lymph node biopsy Lymphadenopathy Disease Asian People immune system diseases Cervical lymphadenopathy Internal medicine Rare case Medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases Histiocytic Necrotizing Lymphadenitis Kikuchi-Fujimoto Disease Lupus erythematosus biology medicine.diagnostic_test business.industry Sentinel Lymph Node Biopsy Raynaud Disease General Medicine medicine.disease Dermatology Rheumatology biology.protein Steroids Antibody medicine.symptom business |
| Zdroj: | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 28(6) |
| ISSN: | 1681-7168 |
| Popis: | Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a self-remitting, immune-mediated rare disorder having unique histopathological characteristics which is commonly seen in young Asian females, but can occur in all ethnicities. There is a strong association between KFD and Systemic Lupus Erythematosus (SLE). We present a case of a young Pakistani boy who presented with cervical lymphadenopathy, fever, blackish discoloration of finger tips, and Raynaud's phenomenon. His lymph node biopsy was suggestive of KFD. The American Rheumatology Association diagnostic criteria were not met as no other features of SLE were present. His autoimmune workup including Anti-Nuclear Antibodies (ANA) and Anti-Double Stranded DNA (Anti-Ds DNA) antibodies were positive and supported the diagnosis of SLE. He improved clinically with steroid therapy and nifedipine with resolution of symptoms. |
| Databáze: | OpenAIRE |
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