Effect of yeast cell wall supplementation on intestinal integrity, digestive enzyme activity and immune traits of broilers
| Autor: | C McCaffrey, R Murphy, A Corrigan, P Moynagh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
040301 veterinary sciences Saccharomyces cerevisiae 0403 veterinary science Sucrase Animal science Cell Wall medicine Animals Gastrointestinal tract Goblet cell biology 0402 animal and dairy science Broiler 04 agricultural and veterinary sciences General Medicine Animal Feed 040201 dairy & animal science Diet medicine.anatomical_structure Dietary Supplements Digestive enzyme biology.protein Alkaline phosphatase Animal Science and Zoology Maltase Digestion Chickens Food Science |
| Zdroj: | British Poultry Science. 62:771-782 |
| ISSN: | 1466-1799 0007-1668 |
| DOI: | 10.1080/00071668.2021.1929070 |
| Popis: | 1. The protective layer formed by intestinal epithelial cells acts as a barrier preventing the adhesion of pathogenic bacteria, aids digestion and passage of nutrients and reduces damage caused from toxins on the gastrointestinal tract. This study was conducted to investigate the effects of a yeast cell wall-based product (YCW), on broiler intestinal integrity, digestive enzyme capacity and immune function.2. A 35-d trial involving 246, one-d-of-hatch male broiler chickens was carried out at a trial facility at Agri-Food Biosciences Institute (AFBI, Belfast, UK). Birds were randomly allocated into 6 pens at day of hatch (41 birds/pen; 123 birds/group). Pens were divided into two groups: (1) basal diet and (2) basal diet that incorporated YCW at the manufacturers' recommended inclusion levels (Alltech Inc., Lexington, Kentucky, USA).3. In this study, YCW supplementation affected broiler intestinal morphology resulting in greater crypt depth, villus height and surface area, goblet cell density and mucus layer thickness and lower muscularis mucosae thickness. The digestive enzymes, maltase, sucrase and alkaline phosphatase, were significantly higher in the YCW supplemented group compared to the control. The expression levels of pro-inflammatory cytokines, IL-1β, IL-12 and IL-18, were significantly lower as was necroptotic cell death in YCW supplemented birds.4. In conclusion, under the conditions of this study, YCW supplementation positively affected intestinal health parameters in broilers following 35-d supplementation. |
| Databáze: | OpenAIRE |
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