Influence of Hydrogen Ions and Neutral Salts upon the Hydration of Interstitial Connective Tissue

Autor: Day Td
Rok vydání: 1948
Předmět:
Zdroj: Nature. 162:152-153
ISSN: 1476-4687
0028-0836
DOI: 10.1038/162152b0
Popis: WHEN a piece of interstitial connective tissue covering the thigh muscles of a rat was placed in water adjusted to pH. 4·5, within a few hours it became opaque, white and shrunken. On the other hand, a piece treated at pH. 11·0 became translucent, grey and swollen. These changes were mutually reversible and could be repeated several times. Observations with the dark-ground microscope showed that this swelling was not due to any change in the collagen fibrils but to a widening of the spaces between them ; shrinkage Was accompanied by an obliteration of such spaces and by a condensation and crimping of the collagen bundles.
Databáze: OpenAIRE