A case of von Hippel–Lindau disease with renal cell carcinoma treated by partial nephrectomy with pre- and post-surgical axitinib therapy
| Autor: | Shoichiro Mukai, Hiroki Takamori, Toshiyuki Kamoto, Naoki Terada, Takahiro Akioka, Toshio Kamimura |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Axitinib Urology medicine.medical_treatment Disease urologic and male genital diseases Renal cell carcinoma medicine Partial nephrectomy Von Hippel–Lindau disease Pre and post neoplasms business.industry medicine.disease Nephrectomy female genital diseases and pregnancy complications Diseases of the genitourinary system. Urology Oncology Tumor progression Von hippel-lindau disease Both kidneys RC870-923 business medicine.drug |
| Zdroj: | Urology Case Reports, Vol 40, Iss, Pp 101925-(2022) Urology Case Reports |
| ISSN: | 2214-4420 |
| Popis: | von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary disease with benign and malignant tumors occurring in various organs including the kidneys. In patients with renal cell carcinoma (RCC) lesions in both kidneys, it is difficult to determine the treatment strategy. We report a case of VHL disease with RCC treated via partial nephrectomy after 6 months of axitinib therapy. Then, the patient continued to receive low-dose axitinib therapy without any signs of tumor progression for 3 years after surgery. Axitinib combined with surgery might be a treatment option for patients with VHL disease harboring bilateral RCC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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