Development and distribution of FMRFamide-like immunoreactivity in the toad (Bufo bufo) brain
| Autor: | L. Iela, M. Di Meglio, Biagio D'Aniello, Maria Fiorentino, Rakesh K. Rastogi, Claudia Pinelli |
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| Přispěvatelé: | Fiorentino, M., C., Pinelli, D'Aniello, Biagio, L., Iela, DI MEGLIO, Maria, Rastogi, RAKESH KUMAR, Pinelli, C., D'Aniello, B., Iela, L., DI MEGLIO, M., Fiorentino, M, Pinelli, Claudia, D'Aniello, B, Iela, L, DI MEGLIO, M, Rastogi, Rk, Iela, Luisa, Rastogi, R. K. |
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Olfactory system
Neuropeptide Toad Bufo bufo Amphibia Placodectomy 03 medical and health sciences Cellular and Molecular Neuroscience Olfactory mucosa Prosencephalon 0302 clinical medicine Olfactory Mucosa biology.animal medicine Animals FMRFamide 030304 developmental biology Neurons 0303 health sciences biology Embryonic origin Cerebrum Olfactory Pathways Immunohistochemistry medicine.anatomical_structure nervous system Hypothalamus Larva Ontogeny Forebrain Neuroscience 030217 neurology & neurosurgery |
| Popis: | By using immunohistochemistry, we studied the development and distribution of the FMRFamide-like immunoreactive (ir) neuronal system in the toad brain during the ontogeny. In addition to this, experimental evidence was provided to show that the rostral forebrain-located FMRFamide neurons originate in the olfactory placode and then migrate into the brain along the olfactory pathway. During early development, within the brain, FMRFamide-ir perikarya first appeared in the periventricular hypothalamus. Later in development, FMRFamide-ir cells were visualized in the rostralmost forebrain simultaneously with similar ir cells in the developing olfactory mucosa. Selective ablation of the olfactory placode(s), prior to the appearance of the first FMRFamide-ir cells in the brain, resulted in the total absence of ir cells in the telencephalon (medial septum and mediobasal telencephalon) of the operated sides(s). The preoptic-suprachiasmatic-infundibular hypothalamus-located FMRFamide-ir neurons were not affected by olfactory placodectomy, arguing that they do not originate in the placode. This result points to the placode as the sole source of such neurons in the rostral forebrain. © 2001 Elsevier Science B.V. |
| Databáze: | OpenAIRE |
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