Current and Emerging Strategies for Prediction and Diagnosis of Prelabour Rupture of the Membranes: A Narrative Review
| Autor: | Saadia Ghafoor |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Amniotic fluid monoclonal/polyclonal antibody immunoassay tests Fern test Review Article Prom Diagnostic tools Chorioamnionitis alpha-fetoprotein biochemical markers medicine Rupture of membranes prelabour rupture of membranes Intensive care medicine PROM Biochemical markers placental alpha microglobulin-1 IL-8 business.industry biomarkers foetal fibronectin preterm prelabour rupture of membranes General Medicine insulin-like growth factor binding protein-1 medicine.disease chorioamnionitis female genital diseases and pregnancy complications amniotic fluid interleukin-8 placental protein 14 Narrative review business |
| Zdroj: | The Malaysian Journal of Medical Sciences : MJMS Saadia Ghafoor |
| ISSN: | 2180-4303 1394-195X |
| Popis: | Prelabour rupture of membranes (PROM) refers to the disruption of foetal membranes before the onset of labour, resulting in the leakage of amniotic fluid. PROM complicates 3% and 8% of preterm and term pregnancies, respectively. Accurate and timely diagnosis is crucial for effective management to prevent adverse maternal- and foetal-outcomes. The diagnosis of equivocal PROM cases with traditional methods often becomes challenging in current obstetrics practice; therefore, various novel biochemical markers have emerged as promising diagnostic tools. This narrative review is sought to review the published data to understand the current and emerging trends in diagnostic modalities in term and preterm pregnancies complicated with PROM and the potential role of various markers for predicting preterm PROM (pPROM) and chorioamnionitis in women with pPROM. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|