Why Do Sex Chromosomes Stop Recombining?
| Autor: | Hanna Sigeman, Jessica K. Abbott, Suvi Ponnikas, Bengt Hansson |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Recombination
Genetic 0106 biological sciences 0301 basic medicine Linkage (software) Sex Chromosomes Genetic Linkage Chromosome Heterozygote advantage Biology Biological Evolution 010603 evolutionary biology 01 natural sciences Population genomics 03 medical and health sciences 030104 developmental biology Meiotic drive Genetic drift Evolutionary biology Genetics Animals Gene Selection (genetic algorithm) |
| Zdroj: | Trends in Genetics |
| ISSN: | 0168-9525 |
| DOI: | 10.1016/j.tig.2018.04.001 |
| Popis: | It is commonly assumed that sex chromosomes evolve recombination suppression because selection favours linkage between sex-determining and sexually antagonistic genes. However, although the role of sexual antagonism during sex chromosome evolution has attained strong support from theory, experimental and observational evidence is rare or equivocal. Here, we highlight alternative, often neglected, hypotheses for recombination suppression on sex chromosomes, which invoke meiotic drive, heterozygote advantage, and genetic drift, respectively. We contrast the hypotheses, the situations when they are likely to be of importance, and outline why it is surprisingly difficult to test them. Lastly, we discuss future research directions (including modelling, population genomics, comparative approaches, and experiments) to disentangle the different hypotheses of sex chromosome evolution. |
| Databáze: | OpenAIRE |
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