Immunological evaluation of cefodizime: A unique molecule among cephalosporins
| Autor: | Labro Mt |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Microbiology (medical)
Bacteria Virulence Phagocyte medicine.drug_class Lymphocyte Cephalosporin Antibiotics Cefotaxime General Medicine Pharmacology Biology Antimicrobial In vitro Cefodizime Infectious Diseases medicine.anatomical_structure Immune system Phagocytosis Immunology medicine Animals Humans Immunologic Factors medicine.drug |
| Zdroj: | Infection. 20:S45-S47 |
| ISSN: | 1439-0973 0300-8126 |
| DOI: | 10.1007/bf01709951 |
| Popis: | The immunomodulatory properties of cefodizime, a new aminothiazolyl cephalosporin, are reviewed. Cefodizime displays in vitro and ex vivo stimulatory effects on phagocyte bactericidal function. It also increases certain lymphocyte responses, including delayed type hypersensitivity and antibody production. In addition, it restores various immune functions in immunocompromised animals and humans. The immunomodulating activity of this drug is further supported by its in vivo efficacy in experimental models of infections using cefodizime-sensitive or -resistant pathogens. Cefodizime appears to be a promising molecule, exhibiting potent antimicrobial activity and exerting potentially beneficial effects on the immune system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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