High 18Fluor-DCFPyL Uptake in Adrenal Adenomas
| Autor: | Sandra Srbljin, Johannes Gerrit Karel Peper, Remco J.J. Knol, Maurits Wondergem, Friso M. van der Zant |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adenoma
Male Agonist Pathology medicine.medical_specialty medicine.drug_class Adrenal Gland Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Antigen Positron Emission Tomography Computed Tomography medicine Humans Urea Adrenal adenoma Radiology Nuclear Medicine and imaging Aged Membrane antigen business.industry Lysine Prostatic Neoplasms Biological Transport General Medicine medicine.disease Ligand (biochemistry) Predictive value 030220 oncology & carcinogenesis business Hormone |
| Zdroj: | Clinical Nuclear Medicine. 42:862-864 |
| ISSN: | 1536-0229 0363-9762 |
| DOI: | 10.1097/rlu.0000000000001808 |
| Popis: | Radioisotope-labeled prostate-specific membrane antigen (PSMA) tracers have been proven accurate for detection of prostate cancer localizations. Uptake of those tracers in other malignant and benign lesions has been reported, including faint accumulation of Ga-PSMA-HBED-CC in adrenal adenoma. A 77-year-old man with prostate carcinoma was scanned with F-DCFPyL, a promising F-labeled PSMA ligand, for prostate-specific antigen progression while on luteinizing hormone-releasing hormone agonist therapy. The PET/CT shows F-DCFPyL uptake in bilateral enlarged adrenals. Non-contrast-enhanced CT scan indicated left adrenal adenoma. Regarding the high positive predictive value of multiphase contrast-enhanced CT (98%), presence of right adrenal adenoma is also likely. |
| Databáze: | OpenAIRE |
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