Ileitis associated with Meckel's diverticulum
| Autor: | Thomas Arnason, Claire M Hamilton |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Histology Muscularis mucosae Adolescent digestive system Gastroenterology Pathology and Forensic Medicine Young Adult Crohn Disease Metaplasia Submucosa Internal medicine Intestine Small otorhinolaryngologic diseases medicine Humans Ileitis Intestinal Mucosa Aged Aged 80 and over Meckel's diverticulum Crohn's disease business.industry General Medicine Middle Aged Hyperplasia medicine.disease digestive system diseases Meckel Diverticulum medicine.anatomical_structure Female medicine.symptom business Diverticulum |
| Zdroj: | Histopathology. 67:783-791 |
| ISSN: | 0309-0167 |
| DOI: | 10.1111/his.12717 |
| Popis: | Aims Histological features of chronic active ileitis in the small intestine neighbouring a Meckel's diverticulum raise the possibility of concurrent Crohn's disease. Several studies have reported a significant association between Meckel's diverticulum and Crohn's disease, whereas some case reports have proposed that the ileitis is attributable to acid-secreting gastric heterotopia. The aim of this study was to evaluate the incidence, histomorphology and clinical follow-up of Meckel's diverticulum-associated ileitis. Methods and results Medical records and slides from 48 consecutive surgical resections performed for Meckel's diverticulum were reviewed. Nine of 48 adults had significant inflammatory changes in the small intestine neighbouring the diverticulum. Two were transmural ulcers attributable to ingestion of a sharp object. Two patients had established Crohn's disease, both with long segments (>95 mm) of transmural inflammation located >100 mm from the diverticulum. The remaining five patients had inflammatory changes (ulceration, pseudopyloric metaplasia, submucosal fibrosis, and muscularis mucosa hyperplasia) confined to a short segment ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |