Comparison of intramuscular versus subcutaneous aqueous progesterone for luteal phase support in artificially prepared frozen embryo transfer cycles

Autor: Meral Gultomruk, Emre Turgut, Mustafa Bahceci, Zalihe Yarkiner, Fazilet Kubra Boynukalin
Rok vydání: 2020
Předmět:
Zdroj: Turkish Journal of Obstetrics and Gynecology
Turkish Journal of Obstetrics and Gynecology, Vol 17, Iss 4, Pp 240-246 (2020)
ISSN: 2149-9330
1307-699X
Popis: Objective: Cryopreservation of embryos for future transfer attempts has noticeably increased in the last decade, especially due to the technological developments in in vitro fertlization (IVF) laboratories. In parallel, different progesterone (P) replacement regimens preceding artificially prepared frozen embryo transfer (AC-FET) attempts, especially with respect to the route of application and dosing scheme, have been widely argued so far. We aimed to provide more information about the efficacy profile of novel subcutaneous aqueous progesterone (SP) in AC-FET cycles. Materials and Methods: This retrospective, single-centre cohort study included a total of 507 AC-FET cycles performed between June 2018 and April 2020. Three hundred forty-nine (68.8%) patients received 50 mg of intramuscular progesterone as once daily, 158 (31.2%) patients received 25 mg of SP as twice daily. Only, the first and single blastocyst transfers from the same cohort were accepted. The inclusion criteria were as follows: females aged
Databáze: OpenAIRE