Obesity: a critical risk factor in the COVID-19 pandemic
| Autor: | Jan Hoong Ho, Salman Razvi, Handrean Soran, Safwaan Adam, See Kwok, Peter M Turkington, Zohaib Iqbal, Carel W. le Roux, Akheel A. Syed |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
obesity
medicine.medical_specialty 030309 nutrition & dietetics Endocrinology Diabetes and Metabolism Pneumonia Viral Respiratory System coronavirus Reviews Endocrine System 030209 endocrinology & metabolism Review Comorbidity medicine.disease_cause Vulnerable Populations immune dysfunction Betacoronavirus 03 medical and health sciences 0302 clinical medicine Immune system Risk Factors Pandemic medicine Humans Risk factor Intensive care medicine Pandemics Coronavirus 0303 health sciences SARS-CoV-2 business.industry COVID-19 SARS‐CoV‐2 | bariatric surgery Thrombosis medicine.disease Obesity Hospitalization Clinical trial Vaccination Immune System Coronavirus Infections business |
| Zdroj: | Kwok, S, Adam, S, Ho, J H, Iqbal, Z, Turkington, P, Razvi, S, le Roux, C, Soran, H & Syed, A 2020, ' Obesity: a critical risk factor in the COVID-19 pandemic ', Clinical Obesity . https://doi.org/10.1111/cob.12403 Clinical Obesity |
| DOI: | 10.1111/cob.12403 |
| Popis: | Summary Obesity is an emerging independent risk factor for susceptibility to and severity of coronavirus disease 2019 (COVID‐19) caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). Previous viral pandemics have shown that obesity, particularly severe obesity (BMI > 40 kg/m2), is associated with increased risk of hospitalization, critical care admission and fatalities. In this narrative review, we examine emerging evidence of the influence of obesity on COVID‐19, the challenges to clinical management from pulmonary, endocrine and immune dysfunctions in individuals with obesity and identify potential areas for further research. We recommend that people with severe obesity be deemed a vulnerable group for COVID‐19; clinical trials of pharmacotherapeutics, immunotherapies and vaccination should prioritize inclusion of people with obesity. |
| Databáze: | OpenAIRE |
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