Right heart thrombus entrapped in patent foramen ovale with pulmonary embolism in a patient with primary hypercoagulable state
| Autor: | Arzu Er, Murathan Küçük, Mustafa Serkan Karakaş, Baris Akdemir, Sinan Cemgil Özbek, Cengiz Ermis, Ali Rıza Gülcan, Refik Emre Altekin, Atakan Yanikoglu |
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| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Dicle Medical Journal, Vol 39, Iss 3, Pp 440-444 (2012) |
| ISSN: | 1308-9889 1300-2945 |
| DOI: | 10.5798/diclemedj.0921.2012.03.0177 |
| Popis: | Thromboembolic disease is a potentially severe pathology.When its clinical feature implies a massive occlusionof the arterial pulmonary tree and a cardiac failure is ensued,it can be seriously life threatening even for youngpatients. Less frequent features as right or left atriumthrombosis could increase morbidity and mortality of thisdisease.We report a case of massive right pulmonary embolism(PE) with entrapped thrombus in patent foramen ovaleand right heart failure in a 32- year-old man. Transthoracicechocardiography showed a right atrial thrombusattached to the inter-atrial septum. Following the diagnosisof right heart thrombosis with massive PE, infusion oftissue type plasminogen activator (100 mg in two hours)was administered. Echocardiography performed two daysafter thrombolysis showed a significant decrease in theright ventricular size and complete lysis of the thrombusin the right heart. By genetic examination, he proved tohave factor V ’Leiden’ gene and two thrombophilia genes,all of which were positive in the heterozygous state. Hehad also a high serum homocysteine.Key words: pulmonary embolism, hypercoagulable state,thrombolytic therapy, patent foramen ovale |
| Databáze: | OpenAIRE |
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