In vivo response to polypropylene following implantation in animal models: a review of biocompatibility
| Autor: | Michelle Kelly, Oluwafisayo Olabisi, Katherine Macdougall, Neil McGuire |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Biocompatibility Urinary Incontinence Stress Urology Biocompatible Materials Urinary incontinence Review Article Polypropylenes Pelvic Organ Prolapse 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine In vivo Obstetrics and Gynaecology Materials Testing Host response medicine Animals Humans Mesh Polypropylene Pelvic organ 030219 obstetrics & reproductive medicine Pelvic floor Stress urinary incontinence business.industry Foreign-Body Reaction Obstetrics and Gynecology Surgical Mesh Surgery Polypropylene mesh Disease Models Animal medicine.anatomical_structure Surgical mesh chemistry 030220 oncology & carcinogenesis Models Animal Female medicine.symptom business |
| Zdroj: | International Urogynecology Journal |
| ISSN: | 1433-3023 0937-3462 |
| DOI: | 10.1007/s00192-016-3029-1 |
| Popis: | Introduction and hypothesis Polypropylene is a material that is commonly used to treat pelvic floor conditions such as pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Owing to the nature of complications experienced by some patients implanted with either incontinence or prolapse meshes, the biocompatibility of polypropylene has recently been questioned. This literature review considers the in vivo response to polypropylene following implantation in animal models. The specific areas explored in this review are material selection, impact of anatomical location, and the structure, weight and size of polypropylene mesh types. Methods All relevant abstracts from original articles investigating the host response of mesh in vivo were reviewed. Papers were obtained and categorised into various mesh material types: polypropylene, polypropylene composites, and other synthetic and biologically derived mesh. Results Polypropylene mesh fared well in comparison with other material types in terms of host response. It was found that a lightweight, large-pore mesh is the most appropriate structure. Conclusion The evidence reviewed shows that polypropylene evokes a less inflammatory or similar host response when compared with other materials used in mesh devices. Electronic supplementary material The online version of this article (doi:10.1007/s00192-016-3029-1) contains supplementary material, which is available to authorized users |
| Databáze: | OpenAIRE |
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