Percutaneous Core Needle Biopsy Can Efficiently and Safely Diagnose Most Primary Bone Tumors

Autor: Marie Karanian, Gualter Vaz, Vincent Crenn, François Gouin, Alexandra Meurgey, Léonard Vezole, Perrine Marec-Bérard, Amine Bouhamama
Rok vydání: 2021
Předmět:
Zdroj: Diagnostics
Volume 11
Issue 9
Diagnostics, Vol 11, Iss 1552, p 1552 (2021)
ISSN: 2075-4418
Popis: A biopsy is a prerequisite for the diagnosis and evaluation of musculoskeletal tumors. It is considered that surgical biopsy provides a more reliable diagnosis because it can obtain more tumor material for pathological analysis. However, it is often associated with a significant complication rate. Imaging-guided percutaneous core needle biopsy (PCNB) is now widely used as an alternative to surgical biopsy
it appears to be minimally invasive, possibly with lower complication rates. This study evaluates the diagnostic yield of the preferred use of PCNB in a referral center, its accuracy, and its complication rate. The data relating to the biopsy and the histological analysis were extracted from the database of a bone tumor reference center where PCNB of bone tumors was discussed as a first-line option. 196 bone tumors were biopsied percutaneously between 2016 and 2020. They were located in the axial skeleton in 21.4% (42) of cases, in the lower limb in 58.7% (115), and in the upper limb in 19.9% (39) cases. We obtained a diagnosis yield of 84.7% and a diagnosis accuracy of 91.7%. The overall complication rate of the percutaneous biopsies observed was 1.0% (n = 2), consisting of two hematomas. PCNB performed in a referral center is a safe, precise procedure, with a very low complication rate, and which avoids the need for first-line open surgical biopsy. The consultation between pathologist, radiologist, and clinician in an expert reference center makes this technique an effective choice as a first-line diagnosis tool.
Databáze: OpenAIRE
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