Coincidental loss of bacterial virulence in multi-enemy microbial communities
| Autor: | Johanna Mappes, Anni-Maria Örmälä-Odegrip, Ji Zhang, Tarmo Ketola, Jouni Laakso |
|---|---|
| Přispěvatelé: | Biosciences |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Ecological selection
Bacteriophage Natural Selection Bacteriophages ANTAGONISTIC COEVOLUTION LISTERIA-MONOCYTOGENES Serratia marcescens 1183 Plant biology microbiology virology Genetics SERRATIA-MARCESCENS Acanthamoeba castellanii 0303 health sciences Multidisciplinary Ecology biology Tetrahymena Medicine Research Article Evolutionary Processes Virulence Factors Antagonistic Coevolution Science Microbial Consortia education Virulence Microbiology Microbial Ecology Evolution Molecular 03 medical and health sciences multi-enemy microbial communities Water environment 030304 developmental biology STAPHYLOCOCCUS-AUREUS Evolutionary Biology PSEUDOMONAS-AERUGINOSA VIRULENCE 030306 microbiology bacterial virulence DICTYOSTELIUM-DISCOIDEUM Biology and Life Sciences Bacteriology biology.organism_classification Organismal Evolution Artificial Selection TETRAHYMENA-THERMOPHILA Evolutionary Ecology Microbial Evolution ta1181 AMEBA ACANTHAMOEBA-CASTELLANII LEGIONELLA-PNEUMOPHILA Bacteria MEDIA COMPOSITION INFLUENCES |
| Zdroj: | PLoS ONE, Vol 9, Iss 11, p e111871 (2014) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | The coincidental virulence evolution hypothesis suggests that outside-host selection, such as predation, parasitism and resource competition can indirectly affect the virulence of environmentally-growing bacterial pathogens. While there are some examples of coincidental environmental selection for virulence, it is also possible that the resource acquisition and enemy defence is selecting against it. To test these ideas we conducted an evolutionary experiment by exposing the opportunistic pathogen bacterium Serratia marcescens to the particle-feeding ciliate Tetrahymena thermophila, the surfacefeeding amoeba Acanthamoeba castellanii, and the lytic bacteriophage Semad11, in all possible combinations in a simulated pond water environment. After 8 weeks the virulence of the 384 evolved clones were quantified with fruit fly Drosophila melanogaster oral infection model, and several other life-history traits were measured. We found that in comparison to ancestor bacteria, evolutionary treatments reduced the virulence in most of the treatments, but this reduction was not clearly related to any changes in other life-history traits. This suggests that virulence traits do not evolve in close relation with these life-history traits, or that different traits might link to virulence in different selective environments, for example via resource allocation trade-offs. peerReviewed |
| Databáze: | OpenAIRE |
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