A case of chemoradiotherapy-associated cardiotoxicity that developed into acute heart failure with progressive subendocardial fibrosis
| Autor: | Takashi Kawasaki, Tsugumi Takayama, Daisuke Yuki, Chizuko Kanbayashi, Nobuaki Sato, Yuji Okura |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Cardiotoxicity Cyclophosphamide business.industry medicine.medical_treatment Subendocardial fibrosis Chemoradiotherapy medicine.disease Article Breast cancer Internal medicine Heart failure Cardiology End-diastolic volume Medicine Cardiology and Cardiovascular Medicine business Endocardium Epirubicin medicine.drug Cardiac catheterization |
| Zdroj: | Journal of Cardiology Cases. 10:115-120 |
| ISSN: | 1878-5409 |
| Popis: | We describe the case of a 61-year-old Japanese woman who developed acute heart failure 5 years after chemoradiotherapy for breast cancer. The patient received less than the cardiotoxic dose of docetaxel, epirubicin, cyclophosphamide, and fluorouracil and experienced no cardiovascular complications in the 5 years between the onset of chemoradiotherapy and the onset of acute heart failure. Cardiac catheterization was performed and elevation of end diastolic pressure of both ventricles was observed. Endomyocardial biopsy showed progressive replacement fibrosis in the subendocardium. Normal thickness of the right endocardium is |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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