Side-to-Side Isoperistaltic Strictureplasty in Extensive Crohn’s Disease
| Autor: | Roger D. Hurst, Michele Rubin, Stephen B. Hanauer, Marcovalerio Melis, Arunas Gasparitis, John Hart, Fabrizio Michelassi, Russell D. Cohen |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Longitudinal study medicine.medical_specialty Radiography medicine.medical_treatment Ileum Resection Jejunum Postoperative Complications Crohn Disease Intestine Small Scientific Papers Strictureplasty Humans Medicine In patient Longitudinal Studies Prospective Studies Crohn's disease business.industry Suture Techniques Middle Aged medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Female Peristalsis business Intestinal Obstruction |
| Zdroj: | Annals of Surgery. 232:401-408 |
| ISSN: | 0003-4932 |
| DOI: | 10.1097/00000658-200009000-00012 |
| Popis: | Objective To report on the results of a prospective longitudinal study of a new bowel-sparing procedure (side-to-side isoperistaltic strictureplasty [SSIS]) in patients with extensive Crohn's disease. Methods Between January 1992 and April 1999, the authors operated on 469 consecutive patients for Crohn's disease of the small bowel. Seventy-one patients (15.1%) underwent at least one strictureplasty; of these, 21 (4.5%; 12 men, 9 women; mean age 39) underwent an SSIS. The long-term changes occurring in the SSIS were studied radiographically, endoscopically, and histopathologically. Results The indication for surgical intervention was symptomatic partial intestinal obstruction in each of the 21 patients. Fourteen SSISs were constructed in the jejunum, four in the ileum, and three with ileum overlapping colon. The average length of the SSIS was 24 cm. Performance of an SSIS instead of a resection resulted in preservation of an average of 17% of small bowel length. One patient suffered a postoperative gastrointestinal hemorrhage. All patients were discharged on oral feedings after a mean of 8 days. In all cases, SSIS resulted in resolution of the preoperative symptoms. With follow-up extending to 7.5 years in 20 patients (one patient died of unrelated causes), radiographic, endoscopic, and histopathologic examination of the SSIS suggests regression of previously active Crohn's disease. Conclusions SSIS is a safe and effective procedure in patients with extensive Crohn's disease. The authors' results provide radiographic, endoscopic, and histopathologic evidence that active Crohn's disease regresses at the site of the SSIS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|