Chromosome banding pattern in human colonic polyps
| Autor: | C. Norryd, H. Dencker, Felix Mitelman, P. G. Nilsson, Joachim Mark, K.-G. Tranberg |
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| Rok vydání: | 2009 |
| Předmět: |
Adenoma
Pathology medicine.medical_specialty Adolescent Colon Biopsy G banding Biology Genetics medicine Humans Polyposis coli Chromosome Aberrations Chromosomes Human 6-12 and X medicine.diagnostic_test Intestinal Polyps Chromosome Karyotype General Medicine medicine.disease digestive system diseases Karyotyping Colonic Neoplasms Female Chromosomes Human 13-15 |
| Zdroj: | Hereditas. 78:63-67 |
| ISSN: | 0018-0661 |
| Popis: | The chromosome pattern was studied by conventional and Giemsa banding techniques in 5 polyps from one patient with polyposis coli and in sporadic adenomas from 4 patients. In both the familial and the non-familial types chromosomal changes preceded histologic signs of invasiveness. In both types preferential engagement of chromosomes Nos. 8 and 14 was found, suggesting a similar chromosomal evolution in colonic adenomas regardless of whether they have a hereditary basis or not. The rate of progression, however, was faster in the familia type of colonic polyps, which may reflect the more malignant potential of these tumors. |
| Databáze: | OpenAIRE |
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