Sex differences in limbic network and risk‐taking propensity in healthy individuals
Autor: | William D.S. Killgore, Sahil Bajaj |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male 0301 basic medicine Multivariate analysis Adolescent Poison control Impulsivity Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience Risk-Taking 0302 clinical medicine Limbic System Humans Medicine Sex Characteristics business.industry Brain morphometry Middle Aged Magnetic Resonance Imaging Curvatures of the stomach 030104 developmental biology Healthy individuals Impulsive Behavior Multiple comparisons problem Female medicine.symptom business Risk taking 030217 neurology & neurosurgery Demography |
Zdroj: | Journal of Neuroscience Research. 98:371-383 |
ISSN: | 1097-4547 0360-4012 |
Popis: | Little is known about the structural neural substrates that may contribute to sex differences in risk-taking propensity (RTP). A close association between risk-seeking behavior and the emotional-regulation network led us to hypothesize that the sex differences in RTP would be associated with sex differences in brain morphometry of the limbic network (LN). We collected RTP scores using the bubble sheet version of the evaluation of risk (EVAR) scale and neuroanatomical data from 57 healthy individuals (29 males). The EVAR scale included sub-scales measuring recklessness/impulsivity, self-confidence, and need for control (NFC). We observed significant sex differences in NFC showing greater desire for control and dominance in males than females (multivariate analysis of covariance, MANCOVAN: p = .01). Morphometry analysis showed that it was only the right LN, which showed significant sex differences in normalized surface area, normalized cortical volume, and adjusted mean curvature index (females > males) at p |
Databáze: | OpenAIRE |
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