Incident CTS in a large pooled cohort study: associations obtained by a Job Exposure Matrix versus associations obtained from observed exposures
| Autor: | Carisa Harris-Adamson, Jay Kapellusch, Alysha R. Meyers, Matthew S. Thiese, Kurt T. Hegmann, Fred Gerr, Angelique Zeringue, Linda Merlino, Arun Garg, Bradley A. Evanoff, Christine C. Ekenga, Barbara Silverstein, Skye Buckner-Petty, Ann Marie Dale, Stephen Bao, David Rempel, Ellen A. Eisen |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
validity
Exposure Assessment Clinical Sciences Job-exposure matrix carpal tunnel syndrome Other Commerce Environmental & Occupational Health 03 medical and health sciences 0302 clinical medicine Occupational epidemiology Clinical Research Environmental health Cox proportional hazards regression 2.1 Biological and endogenous factors Medicine 030212 general & internal medicine Tourism and Services Prospective cohort study Exposure assessment business.industry Prevention Public Health Environmental and Occupational Health 030210 environmental & occupational health job exposure matrix occupational epidemiology Management Public Health and Health Services business exposure-response models Cohort study |
| Zdroj: | Occupational and Environmental Medicine Dale, AM; Ekenga, CC; Buckner-Petty, S; Merlino, L; Thiese, MS; Bao, S; et al.(2018). Incident CTS in a large pooled cohort study: associations obtained by a Job Exposure Matrix versus associations obtained from observed exposures. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 75(7), 501-506. doi: 10.1136/oemed-2017-104744. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6fn6t80x Occupational and environmental medicine, vol 75, iss 7 |
| ISSN: | 1470-7926 1351-0711 |
| Popis: | BackgroundThere is growing use of a job exposure matrix (JEM) to provide exposure estimates in studies of work-related musculoskeletal disorders; few studies have examined the validity of such estimates, nor did compare associations obtained with a JEM with those obtained using other exposures.ObjectiveThis study estimated upper extremity exposures using a JEM derived from a publicly available data set (Occupational Network, O*NET), and compared exposure-disease associations for incident carpal tunnel syndrome (CTS) with those obtained using observed physical exposure measures in a large prospective study.Methods2393 workers from several industries were followed for up to 2.8 years (5.5 person-years). Standard Occupational Classification (SOC) codes were assigned to the job at enrolment. SOC codes linked to physical exposures for forceful hand exertion and repetitive activities were extracted from O*NET. We used multivariable Cox proportional hazards regression models to describe exposure-disease associations for incident CTS for individually observed physical exposures and JEM exposures from O*NET.ResultsBoth exposure methods found associations between incident CTS and exposures of force and repetition, with evidence of dose–response. Observed associations were similar across the two methods, with somewhat wider CIs for HRs calculated using the JEM method.ConclusionExposures estimated using a JEM provided similar exposure-disease associations for CTS when compared with associations obtained using the ‘gold standard’ method of individual observation. While JEMs have a number of limitations, in some studies they can provide useful exposure estimates in the absence of individual-level observed exposures. |
| Databáze: | OpenAIRE |
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