Inflammation and anemia in simple febrile seizures and complex febrile seizures
| Autor: | Ceren Cıralı, Semra Hiz, İpek Polat, Pakize Karaoglu, Müge Ayanoğlu, Uluç Yiş, Erhan Bayram |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Mean corpuscular hemoglobin concentration business.industry Anemia Lymphocyte Red blood cell distribution width General Medicine Hematocrit medicine.disease Gastroenterology medicine.anatomical_structure Febrile seizure Internal medicine medicine Mean platelet volume business Mean corpuscular volume |
| Zdroj: | Annals of Medical Research. 28:1835 |
| ISSN: | 2636-7688 |
| DOI: | 10.5455/annalsmedres.2020.10.1063 |
| Popis: | Aim: This is a unique study that aimed to determine anemia and inflammatory status in simple febrile seizure vs complex febrileseizure patients. Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio are positively correlated with inflammatory markersincluding TNF alpha and IL-6. They are practical, inexpensive, and valuable tools for evaluating inflammation.Materials and Methods: Patients presenting with first febrile seizures were enrolled retrospectively. We investigated hemoglobin,hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration and red blood cell distribution width valuesand white blood cell count, neutrophil, lymphocyte count, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean plateletvolume, C - reactive protein.Results: Our study showed that higher neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and lower mean platelet volumevalues in complex febrile seizure cases than simple febrile seizure cases. We determined cut-off values for neutrophil/lymphocyteratio, platelet/lymphocyte ratio, and mean platelet volume of 2.5, 10523.3, and 7.3 respectively.Conclusion: High neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and low mean platelet volume values can help distinguishsimple febrile seizure and complex febrile seizure patients and predict the clinic. The optimal cut-off values that we determined mayguide clinicians. |
| Databáze: | OpenAIRE |
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