Outcomes based on risk assessment of anastomotic leakage after rectal cancer surgery
| Autor: | Dong-Feng Wang, Dong-Zheng Li, Bei-Cheng Sun, Xin-En Huang, Xin Guan, Liu Yang, Jian-Nong Zhou, Dong-Sheng Yu, Xin Zhou, Jian-ping Gong |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Epidemiology Colorectal cancer Anastomotic Leak Anastomosis Adenocarcinoma Gastroenterology Risk Assessment Postoperative Complications Risk Factors Internal medicine medicine Humans Prospective Studies Prospective cohort study Survival rate Survival analysis Digestive System Surgical Procedures Aged Neoplasm Staging Proportional hazards model business.industry Rectal Neoplasms Anastomosis Surgical Public Health Environmental and Occupational Health Middle Aged medicine.disease Prognosis Total mesorectal excision Surgery Survival Rate Oncology Female business Body mass index Follow-Up Studies |
| Zdroj: | Asian Pacific journal of cancer prevention : APJCP. 15(2) |
| ISSN: | 2476-762X |
| Popis: | Purpose: Anastomotic leakage (AL) is associated with high morbidity and mortality, high reoperation rates, and increased hospital length of stay. Here we investigated the risk factors for AL after anterior resection for rectal cancer with a double stapling technique. Patients and Methods: Data for 460 patients who underwent primary anterior resection with a double stapling technique for rectal carcinoma at a single institution from 2003 to 2007 were prospectively collected. All patients experienced a total mesorectal excision (TME) operation. Clinical AL was defined as the presence of leakage signs and confirmed by diagnostic work-up according to ICD-9 codes 997.4, 567.22 (abdominopelvic abscess), and 569.81 (fistula of the intestine). Univariate and logistic regression analyses of 20 variables were undertaken to determine risk factors for AL. Survival was analysed using the Cox regression method. Results: AL was noted in 35 (7.6%) of 460 patients with rectal cancer. Median age of the patients was 65 (50-74) and 161 (35%) were male. The diagnosis of AL was made between the 6th and 12th postoperative day (POD; mean 8th POD). After univariate and multivariate analysis, age (p=0.004), gender (p=0.007), tumor site (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|