Delayed Diagnosis and Treatment of a Critically Ill Patient with Infective Endocarditis Due to a False-Positive Molecular Diagnostic Test for SARS-CoV-2

Autor: Ilias Samiotis, Nikolaos Schizas, Konstantinos Papakonstantinou, Michail Argiriou, Panagiotis Dedeilias, Vasilios Patris, Theodoros Michailidis
Rok vydání: 2020
Předmět:
Male
medicine.medical_specialty
Delayed Diagnosis
Fever
Critical Illness
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Aortic Valve Insufficiency
Pneumonia
Viral
030204 cardiovascular system & hematology
Antibodies
Viral
Real-Time Polymerase Chain Reaction
Delayed diagnosis
Risk Assessment
Serology
03 medical and health sciences
COVID-19 Testing
0302 clinical medicine
Pandemic
medicine
Humans
Endocarditis
False Positive Reactions
Cardiac Surgical Procedures
Intensive care medicine
Pandemics
Clinical Laboratory Techniques
business.industry
COVID-19
Diagnostic test
Articles
Endocarditis
Bacterial
General Medicine
Middle Aged
Prognosis
medicine.disease
Coronavirus
Dyspnea
Treatment Outcome
030220 oncology & carcinogenesis
Infective endocarditis
Disease Progression
Coronavirus Infections
Risk assessment
business
Zdroj: The American Journal of Case Reports
ISSN: 1941-5923
Popis: Patient: Male, 53-year-old Final Diagnosis: Infective endocarditis Symptoms: Dynpnea • fever Medication:— Clinical Procedure: Surgical aortic valve replacement Specialty: Cardiac surgery Objective: Challenging differential diagnosis Background: The worldwide spread of the severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) has created unprecedented situations for healthcare professionals and healthcare systems. Although infection with this virus is considered the main health problem currently, other diseases are still prevalent. Case Report: This report describes a 59-year-old man who presented with symptoms of dyspnea and fever that were attributed to Covid-19 infection. His clinical condition deteriorated and further examinations revealed a subjacent severe aortic regurgitation due to acute infective endocarditis. Surgical treatment was successful. Conclusions: The results of diagnostic tests for Covid-19 should be re-evaluated whenever there are clinical mismatches or doubts, as false-positive Covid-19 test results can occur. Clinical interpretation should not be determined exclusively by the Covid-19 pandemic. This case report highlights the importance of using validated and approved serological and molecular testing to detect infection with SARS-CoV-2, and to repeat tests when there is doubt about presenting symptoms.
Databáze: OpenAIRE
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