Sensitivity of the phage and complementary strands of the replicative form of phage phi X 174 deoxyribonucleic acid to ultra-violet light

Autor:	Iliashenko Bn
Rok vydání:	1966
Předmět:	Infectivity Multidisciplinary biology Ultraviolet Rays Phagemid Phi X 174 biology.organism_classification Coliphages Thymine Radiation Effects chemistry.chemical_compound chemistry Biochemistry Complementary DNA DNA Viral Nucleic acid Cytosine DNA
Zdroj:	Nature. 211(5047)
ISSN:	0028-0836
Popis:	PHOTOPRODUCTS of pyrimidines are known to play an important part in the inactivation of nucleic acids by ultra-violet light. The replicative form (RF) of phage φ X 174 DNA is a convenient material to use for an investigation of the dependence of DNA ultra-violet sensitivity on base composition. The properties of both strands of RF DNA are similar, yet their nucleotide composition differs: the complementary strand contains 8.2 per cent less thymine and 5.6 per cent more cytosine than the phage strand1,2. The present investigation was undertaken to compare the ultra-violet inactivation of the infectivity of both chains of RF φ X 174 DNA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e2368ea781583db3900397f36429b4 https://pubmed.ncbi.nlm.nih.gov/5967842 Zobrazit plný text záznamu