Minor alkaloids from an aqueous extract of the hook-bearing stem of Uncaria rhynchophylla
| Autor: | Cheng-Gen Zhu, Jiangong Shi, Chengbo Xu, Qing-Lan Guo, Ruo-Fei Li |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pharmacology
Aqueous extract Rubiaceae Traditional medicine biology 010405 organic chemistry Chemistry Uncaria rhynchophylla Monoterpene Organic Chemistry Pharmaceutical Science Decoction General Medicine biology.organism_classification 01 natural sciences 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry Complementary and alternative medicine Drug Discovery Molecular Medicine |
| DOI: | 10.6084/m9.figshare.14363014.v1 |
| Popis: | Seven new monoterpene alkaloids (1−7), along with 18 known analogues, were isolated from an aqueous decoction of the hook-bearing stems of Uncaria rhynchophylla (Gou-teng). Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Compound 1 is the first monoterpene 22-norindoloquinolizidine alkaloid with a ketene unit, while 2 and 3 are unusual indoloquinolizidine alkaloids having an oxazinane ring. |
| Databáze: | OpenAIRE |
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