Day-long glucose, insulin, and fructose responses of hyperinsulinemic and nonhyperinsulinemic men adapted to diets containing either fructose or high-amylose cornstarch
| Autor: | A S Powell, Daniel J. Scholfield, J J Canary, Sheldon Reiser, Meira Fields, P Panda |
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| Rok vydání: | 1989 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Erythrocytes Time Factors medicine.medical_treatment Medicine (miscellaneous) Fructose Biology chemistry.chemical_compound Hyperinsulinism Internal medicine Dietary Carbohydrates medicine Hyperinsulinemia Humans Insulin Pancreatic hormone Glucose tolerance test Nutrition and Dietetics medicine.diagnostic_test Starch Metabolism Glucose Tolerance Test Middle Aged Carbohydrate medicine.disease Receptor Insulin Endocrinology chemistry Amylose |
| Zdroj: | The American Journal of Clinical Nutrition. 50:1008-1014 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/50.5.1008 |
| Popis: | Ten hyperinsulinemic and 11 nonhyperinsulinemic men consumed a typical American diet containing 20% of calories either as fructose or as high-amylose cornstarch for 5 wk in a crossover design to determine their effects on indices of glucose tolerance. Blood glucose, insulin, and fructose were determined before and 30, 60, 90, 120 and 180 min after breakfast, lunch, and dinner. Glucose responses were significantly lower 60 and 120 min and the insulin response lower 60 min after the meals containing fructose. Hyperinsulinemic men showed a tendency toward decreased insulin sensitivity after consuming fructose on the basis of an increased insulin-to-glucose ratio and decreased insulin binding to erythrocytes. These results generally show a beneficial effect of fructose on glucose tolerance; however, recommendations for including large amounts of fructose in the diet should also be based on a complete evaluation of the effect on other metabolic risk factors. |
| Databáze: | OpenAIRE |
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