High-flow nasal cannula compared with continuous positive airway pressure: a bench and physiological study

Autor: Fernando Vieira, Frank Silva Bezerra, Remi Coudroy, Annia Schreiber, Irene Telias, Sebastián Dubo, Giulia Cavalot, Sergio Martins Pereira, Thomas Piraino, Laurent Jean Brochard
Rok vydání: 2022
Předmět:
Zdroj: Journal of Applied Physiology. 132:1580-1590
ISSN: 1522-1601
8750-7587
Popis: High-flow nasal cannula (HFNC) is extensively used for acute respiratory failure. However, questions remain regarding its physiological effects. We explored 1) whether HFNC produced similar effects to continuous positive airway pressure (CPAP); 2) possible explanations of respiratory rate changes; 3) the effects of mouth opening. Two studies were conducted: a bench study using a manikin's head with lungs connected to a breathing simulator while delivering HFNC flow rates from 0 to 60L/min; a physiological cross-over study in 10 healthy volunteers receiving HFNC (20 to 60L/min) with the mouth open or closed and CPAP 4cmH
Databáze: OpenAIRE