Intrasurgical Pancreas Cytology

Autor: Hans Bosseckert, Gertje Penzlin, Falk Arnold, Harald Schramm, Holger Urban
Rok vydání: 2002
Předmět:
Zdroj: Pancreas. 24:210-214
ISSN: 0885-3177
DOI: 10.1097/00006676-200203000-00014
Popis: Introduction A differential therapy of chronic pancreatitis and carcinoma calls for evaluation of the validity of findings. Presurgical suspicion of a carcinoma often requires intrasurgical diagnostics such as excisional biopsies, punch biopsies, and fine-needle aspiration cytology (FNAC) for confirmation. Aims To evaluate FNAC as an intraoperative diagnostic method of very high probability. Methodology Intrasurgical fine-needle aspiration biopsy and cytologic assessment were carried out in 474 patients. The indications for operative therapy and FNAC were suspicion of pancreatic tumor, chronic pancreatitis even without suspicion of tumor, and pathologic alterations found during other surgeries in the upper abdomen. Results The level of sensitivity was 93.1%, specificity was 99.1%, predictive value of positive results was 99.2% and of negative results was 92.1%. Conclusion FNAC is a suitable method for intrasurgical confirmation of pancreatic carcinoma. It can be performed safely, effectively, and rapidly.
Databáze: OpenAIRE