Determination of Immunoglobulin A against Gardnerella vaginalis Hemolysin, Sialidase, and Prolidase Activities in Vaginal Fluid: Implications for Adverse Pregnancy Outcomes
| Autor: | Poul Thorsen, Sabina Cauci, Secondo Guaschino, Annie Bremmelgaard, Diana Schendel, Franco Quadrifoglio |
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| Přispěvatelé: | Cauci, S, Thorsen, P, Schendel, De, Bremmelgaard, A, Quadrifoglio, F, Guaschino, Secondo |
| Rok vydání: | 2003 |
| Předmět: |
Adult
Microbiology (medical) Immunoglobulin A Dipeptidases Neuraminidase Biology medicine.disease_cause Sialidase Hemolysin Proteins Vaginal disease Pregnancy medicine Humans Gardnerella vaginalis Antigens Bacterial Pregnancy Outcome Bacteriology Vaginosis Bacterial medicine.disease Pregnancy Complications Low birth weight Immunology biology.protein Gestation Female Bacterial vaginosis medicine.symptom |
| Zdroj: | Aarhus University Cauci, S, Thorsen, P, Schendel, D E, Bremmelgaard, A, Quadrifoglio, F & Guaschino, S 2003, ' Determination of Immunoglobulin A against Gardnerella vaginalis Hemolysin, Sialidase, and Prolidase Activities in Vaginal Fluid: Implications for Adverse Pregnancy Outcomes ', Journal of Clinical Microbiology, vol. 41, no. 1, pp. 435-438 . |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.41.1.435-438.2003 |
| Popis: | A nested case-control study of low birth weight and preterm delivery was performed with singleton women. Immunoglobulin A (IgA) against the Gardnerella vaginalis hemolysin (anti-Gvh IgA) and sialidase and prolidase activities were determined in vaginal fluid at 17 weeks of gestation. Sialidase positivity and bacterial vaginosis with high prolidase activity were associated with 2- and 11-fold increased risks for low birth weight, respectively. No woman with bacterial vaginosis plus a strong anti-Gvh IgA response had an adverse outcome. |
| Databáze: | OpenAIRE |
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